SCHEMBL6827159

SCHEMBL6827159

C=C(CCCC)C(=O)NC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.40
TYRO3 Q06418 1/20 0.40
MERTK Q12866 1/20 0.40
GAS6 Q14393 1/20 0.40
EPHX2 P34913 4/20 0.34
EPHX1 P07099 3/20 0.34
HDAC4 P56524 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
GNAI3 P08754 2/20 0.31
GNAO1 P09471 2/20 0.31
GNAI1 P63096 2/20 0.31
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829298 0.91 FLT3 (0.37) FLT3TYRO3MERTKGAS6EPHX2
SCHEMBL107837 0.77 HDAC4 (0.36) FLT3TYRO3MERTKGAS6HDAC4
SCHEMBL10719860 0.77 GNAI3 (0.52) EPHX2GNAI3GNAO1GNAI1MEN1
SCHEMBL8435486 0.77 GNAI3 (0.52) EPHX2GNAI3GNAO1GNAI1MEN1
SCHEMBL11371496 0.76 EPHX2 (0.32) EPHX2EPHX1MEN1POLBMAPT
SCHEMBL9150705 0.73 HDAC4 (0.37) FLT3TYRO3MERTKGAS6HDAC4
SCHEMBL13298035 0.72 SMN1; SMN2 (0.47) FLT3TYRO3MERTKGAS6EPHX2
SCHEMBL9580854 0.72 TRPV1 (0.34) EPHX2EPHX1GNAI3GNAO1GNAI1
SCHEMBL8771887 0.72 MAOB (0.37) FLT3TYRO3MERTKGAS6HDAC4
SCHEMBL10721660 0.71 EPHX1 (0.60) EPHX2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6737528-B2 Vinylic hindered amine light stabilizers COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-05-18 US claimed
US-5476882-A Containing 2,2,6,6-tetraalkylpiperidine derivative CIBA-GEIGY CORPORATION (US) 1995-12-19 US disclosed
US-5274016-A Crosslinked polyolefin core and stabilizer of a 2,2,6,6-tetramethylpiperidine derivative having at least one ethylenic double bone CIBA-GEIGY CORPORATION (US) 1993-12-28 US disclosed
EP-0296391-B1 LIGHT-STABILIZED POLYMER MICROPARTICLES CONTAINING EPOXY GROUPS CIBA-GEIGY AG (CH) 1993-07-07 EP disclosed
EP-0337431-B1 STABILIZED STYRENE COPOLYMER COMPRISING ELASTOMER PARTICLES CIBA-GEIGY AG (CH) 1993-06-23 EP disclosed
EP-0293871-B1 LIGHT STABILIZED, STARSHAPED MICROPARTICLES CIBA-GEIGY AG (CH) 1993-03-17 EP disclosed
US-5135986-A Graft polymers of styrene or A-methylstyrene and a comonomer on a core of elastomer modified by a steric hindered unsaturated 2,2,6,6-tetramethylpiperidine compoune; photostability CIBA-GEIGY CORPORATION (US) 1992-08-04 US disclosed
EP-0226538-B1 LIGHT STABILIZED POLYMER MICROPARTICLES Ciba SC Holding AG (CH) 1991-09-11 EP disclosed
US-4894399-A Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY CORPORATION (US) 1990-01-16 US disclosed
US-4880859-A GROUP TRANSFER POLYMERIZATION, COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 US disclosed
EP-0337431-A2 Stabilized styrene copolymer comprising elastomer particles CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed
EP-0296391-A2 Light-stabilized polymer microparticles containing epoxy groups CIBA-GEIGY AG (CH) 1988-12-28 EP disclosed
EP-0293871-A2 Light stabilized, starshaped microparticles CIBA-GEIGY AG (CH) 1988-12-07 EP disclosed
EP-0114784-B1 ELECTRON-BEAM CURING METHOD FOR COATINGS CIBA-GEIGY AG (CH) 1988-06-01 EP disclosed
EP-0226538-A2 Light stabilized polymer microparticles CIBA-GEIGY AG (CH) 1987-06-24 EP disclosed
US-4511596-A 2,2,6,6-TETRAALKYLPIPERIDINE DERIVATIVES AS CURING PROMOTERS CIBA-GEIGY CORPORATION (US) 1985-04-16 US disclosed
EP-0114784-A2 Electron-beam curing method for coatings CIBA-GEIGY AG (CH) 1984-08-01 EP disclosed