Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 13/20 | 0.61 |
| ▸ | POLB | P06746 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GRK6 | P43250 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686171 | 0.85 | AR (0.84) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL15299952 | 0.85 | AR (0.81) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL15300156 | 0.85 | AR (0.81) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL13601355 | 0.82 | AR (0.79) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL15300175 | 0.81 | MAPT (0.78) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL19406536 | 0.81 | AR (0.80) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL683115 | 0.80 | MAPT (0.58) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL914607 | 0.79 | AR (0.81) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL15321707 | 0.77 | AR (0.60) | ARMAPTPOLBMEN1KMT2A | |
| SCHEMBL15322842 | 0.77 | AR (0.60) | ARMAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010233-A1 | METHODS AND COMPOSITIONS TO INHIBIT EDEMA FACTOR AND ADENYLYL CYCLASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010233-A1 | METHODS AND COMPOSITIONS TO INHIBIT EDEMA FACTOR AND ADENYLYL CYCLASE | VIP, PDE3B, ADCY5 | AR 4834/4885MAPT 4872/4885POLB 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.