Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYBB | P04839 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285775 | 0.82 | MAPT (0.74) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL678910 | 0.82 | MAPT (0.74) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL682724 | 0.80 | AR (0.74) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL677473 | 0.77 | MAPT (0.63) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL15300175 | 0.76 | MAPT (0.78) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL5993987 | 0.76 | USP7 (0.69) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL5303202 | 0.74 | MAPT (0.61) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL914607 | 0.72 | AR (0.81) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL5522946 | 0.72 | CA12 (0.70) | MAPTTDP1HSPA1APTPN7L3MBTL1 | |
| SCHEMBL15321272 | 0.72 | MAPT (0.77) | MAPTTDP1HSPA1APTPN7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010233-A1 | METHODS AND COMPOSITIONS TO INHIBIT EDEMA FACTOR AND ADENYLYL CYCLASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010233-A1 | METHODS AND COMPOSITIONS TO INHIBIT EDEMA FACTOR AND ADENYLYL CYCLASE | VIP, PDE3B, ADCY5 | MAPT 4872/4885TDP1 3880/4885HSPA1A 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.