SCHEMBL13601355

SCHEMBL13601355

COC(=O)c1ccc2c(c1)C1C=CCC1C(c1ccccc1)N2

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.79
MAPT P10636 10/20 0.67
KDM4E B2RXH2 4/20 0.67
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
ALDH1A1 P00352 3/20 0.67
ALOX12 P18054 1/20 0.67
HTT P42858 1/20 0.67
HPGD P15428 1/20 0.66
RAB9A P51151 1/20 0.66
POLB P06746 4/20 0.66
GAA P10253 1/20 0.66
PKM P14618 1/20 0.66
RECQL P46063 1/20 0.66
GRK6 P43250 1/20 0.62
GAPDH P04406 1/20 0.61
HSPA1A P0DMV8 1/20 0.61
PTPN7 P35236 1/20 0.61
NR4A1 P22736 1/20 0.59
USP7 Q93009 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686171 0.90 AR (0.84) ARMAPTKDM4EMEN1KMT2A
SCHEMBL14582287 0.88 KMT2A (0.80) ARMAPTKDM4EMEN1KMT2A
SCHEMBL23949811 0.88 MAPT (0.81) ARMAPTKDM4EMEN1KMT2A
SCHEMBL681674 0.88 MAPT (0.81) ARMAPTKDM4EMEN1KMT2A
SCHEMBL15300156 0.86 AR (0.81) ARMAPTKDM4EMEN1KMT2A
SCHEMBL15299952 0.86 AR (0.81) ARMAPTKDM4EMEN1KMT2A
SCHEMBL19406536 0.84 AR (0.80) ARMAPTKDM4EMEN1KMT2A
SCHEMBL13608010 0.83 AR (0.76) ARMAPTKDM4EMEN1KMT2A
SCHEMBL13601360 0.83 AR (0.75) ARMAPTKDM4EMEN1KMT2A
SCHEMBL682724 0.82 AR (0.74) ARMAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9452425-B2 Compositions containing ionic liquids and their uses, in particular in organic synthesis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-09-27 US disclosed
US-9452425-B2 Compositions containing ionic liquids and their uses, in particular in organic synthesis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-09-27 US disclosed
US-20090326228-A1 COMPOSITIONS CONTAINING IONIC LIQUIDS AND THEIR USES, IN PARTICULAR IN ORGANIC SYNTHESIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-12-31 US disclosed
US-20090326228-A1 COMPOSITIONS CONTAINING IONIC LIQUIDS AND THEIR USES, IN PARTICULAR IN ORGANIC SYNTHESIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-12-31 US disclosed
US-20070043234-A1 Use of functionalized onium salts as a soluble support for organic synthesis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2007-02-22 US disclosed
US-20070043234-A1 Use of functionalized onium salts as a soluble support for organic synthesis CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090326228-A1 COMPOSITIONS CONTAINING IONIC LIQUIDS AND THEIR USES, IN PARTICULAR IN ORGANIC SYNTHESIS F12, ANXA1, F11 AR 3458/4885MAPT 2026/4885KDM4E 4820/4885
US-20070043234-A1 Use of functionalized onium salts as a soluble support for organic synthesis NOS1, NOS2, F12 AR 1848/4885MAPT 862/4885KDM4E 4485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.