Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | CEL | P19835 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 4/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827603 | 0.98 | TDP1 (0.49) | TDP1MEN1GLACYP3A4KMT2A | |
| SCHEMBL6827998 | 0.98 | TDP1 (0.49) | TDP1MEN1GLACYP3A4KMT2A | |
| SCHEMBL17292459 | 0.96 | TDP1 (0.50) | TDP1MEN1GLACYP3A4KMT2A | |
| SCHEMBL1263377 | 0.92 | TDP1 (0.53) | TDP1MEN1GLACYP3A4KMT2A | |
| SCHEMBL6827962 | 0.85 | TDP1 (0.47) | TDP1MEN1GLACYP3A4KMT2A | |
| SCHEMBL6827433 | 0.80 | TDP1 (0.43) | TDP1MEN1GLACYP3A4KMT2A | |
| SCHEMBL6829521 | 0.77 | CYP1B1 (0.38) | TDP1MEN1KMT2ACYP1B1CEL | |
| SCHEMBL6827665 | 0.77 | CYP1B1 (0.41) | TDP1KMT2ACYP1B1CELHDAC4 | |
| SCHEMBL6829397 | 0.76 | CYP1B1 (0.40) | TDP1MEN1KMT2ACYP1B1CEL | |
| SCHEMBL6824269 | 0.76 | CYP1B1 (0.40) | TDP1MEN1KMT2ACYP1B1CEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| CN-1236357-A | Aminomethylene derivatives and ultraviolet absorber comprising the same | CHEMIPRO KASEI KAISHA LTD (JP) | 1999-11-24 | — | — | CN | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |