Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791221 | 0.94 | MAPK1 (0.47) | MAPK1NPSR1L3MBTL1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL6720251 | 0.92 | MAPK1 (0.46) | MAPK1NPSR1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL4192847 | 0.84 | MAPK1 (0.47) | MAPK1NPSR1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2272643 | 0.82 | RBP4 (0.53) | KMT2AMAPT | |
| SCHEMBL2278132 | 0.82 | CCR5 (0.42) | KMT2AALDH1A1MAPT | |
| SCHEMBL2719593 | 0.81 | RBP4 (0.41) | KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL12396714 | 0.80 | MEN1 (0.46) | KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2062184 | 0.79 | CHRNB4 (0.47) | KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL2274616 | 0.79 | MEN1 (0.60) | NPSR1KMT2AALDH1A1MAPT | |
| SCHEMBL23348064 | 0.78 | PROKR1 (0.50) | KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010943-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |