Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.88 |
| ▸ | MPC2 | O95563 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clx-0921 SCHEMBL3794534 | 0.93 | PPARG (1.00) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| Clx-0921 SCHEMBL3798951 | 0.93 | PPARG (1.00) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| Clx-0921 SCHEMBL3794540 | 0.93 | PPARG (1.00) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL12631345 | 0.90 | PPARG (0.86) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL3802909 | 0.89 | PPARG (0.78) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL3802907 | 0.89 | PPARG (0.78) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL13347275 | 0.89 | PPARG (0.78) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL3792638 | 0.86 | PPARG (0.83) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL3792635 | 0.86 | PPARG (0.83) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL4434725 | 0.85 | PPARG (0.84) | PPARGMPC2CYP2C8CYP2C9FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186299-A1 | Novel heterocyclic analogs of diphenylethylene compounds | THERACOS, INC. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186299-A1 | Novel heterocyclic analogs of diphenylethylene compounds | FFAR2, GPR119, FFAR4 | PPARG 25/4885MPC2 154/4885CYP2C8 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.