Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263377 | 0.87 | TDP1 (0.53) | TDP1CYP3A4MEN1GLAKMT2A | |
| SCHEMBL6829594 | 0.81 | MAPT (0.34) | MAPTSTAT1DAO | |
| SCHEMBL6829613 | 0.80 | TDP1 (0.50) | TDP1CYP3A4MEN1GLAKMT2A | |
| SCHEMBL17292459 | 0.80 | TDP1 (0.50) | TDP1CYP3A4MEN1GLAKMT2A | |
| SCHEMBL6827603 | 0.78 | TDP1 (0.49) | TDP1CYP3A4MEN1GLAKMT2A | |
| SCHEMBL6827998 | 0.78 | TDP1 (0.49) | TDP1CYP3A4MEN1GLAKMT2A | |
| SCHEMBL6827962 | 0.77 | TDP1 (0.47) | TDP1CYP3A4MEN1GLAKMT2A | |
| SCHEMBL6827712 | 0.71 | SMPD3 (0.39) | CYP3A4BRD4ALDH1A1 | |
| SCHEMBL6827261 | 0.65 | MAPT (0.38) | TDP1MAPT | |
| SCHEMBL1516129 | 0.64 | ESR2 (0.62) | CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |