Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363303 | 0.88 | FFAR1 (0.56) | FFAR1ALOX5LTB4RLTB4R2KDM4E | |
| SCHEMBL6904351 | 0.83 | FFAR1 (0.61) | FFAR1ALOX5LTB4RLTB4R2KDM4E | |
| Methacrylic Acid SCHEMBL5095488 | 0.80 | FFAR1 (0.55) | FFAR1ALOX5LTB4RLTB4R2HPGD | |
| SCHEMBL11853864 | 0.80 | FFAR1 (0.54) | FFAR1ALOX5LTB4RLTB4R2S1PR5 | |
| Sulfuric Acid SCHEMBL27781775 | 0.80 | KMT2A (0.46) | KDM4EGMNNALDH1A1LMNAPOLB | |
| SCHEMBL14942091 | 0.79 | GAA (0.54) | FFAR1ALOX5LTB4RLTB4R2S1PR5 | |
| SCHEMBL27980861 | 0.78 | ALOX5 (0.50) | FFAR1ALOX5LTB4RLTB4R2KDM4E | |
| SCHEMBL10767870 | 0.78 | FFAR1 (0.57) | FFAR1ALOX5LTB4RLTB4R2KMT2A | |
| SCHEMBL10148418 | 0.78 | KMT2A (0.65) | FFAR1ALOX5LTB4RLTB4R2KMT2A | |
| SCHEMBL10148419 | 0.78 | KMT2A (0.65) | FFAR1ALOX5LTB4RLTB4R2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115336589-A | High-efficiency weeding composition for preventing and removing weeds in paddy fields and preparation thereof | 南通江山农药化工股份有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115336589-A | High-efficiency weeding composition for preventing and removing weeds in paddy fields and preparation thereof | 南通江山农药化工股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| US-6743820-B2 | ADMINISTERING TO THE EPITHELIUM AN EFFECTIVE AMOUNT OF AN AGENT COMPRISING: A) AT LEAST ONE AROMATIC GROUP; B) AT LEAST ONE SULFATE OR METALSULFATE GROUP AND C) A SUBSTITUENT GROUPS ON THE RING | UNIVERSITY OF TOLEDO | 2004-06-01 | — | — | US | disclosed |
| US-20020052408-A1 | Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-05-02 | — | — | US | disclosed |
| WO-2002004411-A1 | METHODS FOR PROTECTION OF STRATIFIED SQUAMOUS EPITHELIUM AGAINST INJURY BY NOXIOUS SUBSTANCES AND NOVEL AGENTS FOR USE THEREFOR | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052408-A1 | Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor | HRH2, NR1H4, NCEH1 | SCN3A 1091/4885FFAR1 176/4885ALOX5 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.