Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1499046 | 0.80 | TP53 (0.41) | ALDH1A1TP53GAAMAPTHSD17B10 | |
| SCHEMBL1499025 | 0.78 | TDP1 (0.56) | KDM4EALDH1A1TP53GAAMAPT | |
| SCHEMBL6827556 | 0.78 | PDE4A (0.44) | KDM4EGAAHSD17B10 | |
| SCHEMBL1499114 | 0.78 | DDB1 (0.44) | DDB1CRBNKDM4EALDH1A1TSHR | |
| SCHEMBL1498959 | 0.78 | DDB1 (0.44) | DDB1CRBNKDM4EALDH1A1TSHR | |
| SCHEMBL2200068 | 0.77 | KDM4E (0.46) | DDB1CRBNKDM4EALDH1A1TP53 | |
| SCHEMBL14492202 | 0.76 | ALDH1A1 (0.55) | DDB1CRBNKDM4EALDH1A1GAA | |
| SCHEMBL7167696 | 0.75 | ALDH1A1 (0.67) | DDB1CRBNKDM4EALDH1A1TP53 | |
| SCHEMBL7046333 | 0.74 | TNKS2 (0.57) | DDB1CRBNKDM4EALDH1A1TP53 | |
| SCHEMBL3657517 | 0.73 | CRBN (0.58) | DDB1CRBNKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004009559-A2 | DIHYDROURACIL COMPOUNDS AS ANTI-ICTOGENIC OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-01-29 | — | — | WO | disclosed |