Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | MPI | P34949 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536959 | 0.85 | KDM4E (0.56) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL13527924 | 0.84 | TDP1 (0.80) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL14467187 | 0.82 | ALDH1A1 (0.76) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL31312297 | 0.82 | ALDH1A1 (0.76) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL11652811 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL17570757 | 0.81 | MAPT (0.61) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL11153022 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL11647775 | 0.80 | DDB1 (0.56) | ALDH1A1MAPTLMNAGAADDB1 | |
| SCHEMBL9690927 | 0.79 | TDP1 (0.67) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL14466166 | 0.79 | TDP1 (0.67) | ALDH1A1MAPTLMNAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566105-B1 | Generation of preferential amino acids in sample; obtain racemic mixture of hydantoin, incubate with genetically engineered microorganism, recover amino acids | ENIRICERCHE S.P.A. (IT) | 2003-05-20 | — | — | US | claimed |
| EP-0775748-B1 | Preparation of D-alpha-amino acids, using bacteria transformed with the carbamoylase-hydantoinase operon | ENITECNOLOGIE SPA (IT) | 2002-11-20 | — | — | EP | claimed |
| US-5834258-A | STEREOSELECTIVE CONVERSION OF RACEMIC MIXTURES OF 5-SUBSTITUTED HYDANTOINS WITH ENZYME | ENIRICERCHE S.P.A. (IT) | 1998-11-10 | — | — | US | claimed |
| EP-0677585-B1 | Process for the production of D-alpha-amino acids | ENIRICERCHE SPA (IT) | 1997-07-23 | — | — | EP | claimed |
| EP-0775748-A2 | Preparation of D-alpha-amino acids, using bacteria transformed with the carbamoylase-hydantoinase operon | ENIRICERCHE S.p.A. (IT) | 1997-05-28 | — | — | EP | claimed |
| EP-0677585-A1 | Process for the production of D-alpha-amino acids | ENIRICERCHE S.p.A. (IT) | 1995-10-18 | — | — | EP | claimed |
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | claimed |
| US-20240390488-A1 | METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND MEK INHIBITORS | GENENTECH, INC. (US) | 2024-11-28 | — | — | US | disclosed |
| US-6566105-B1 | Generation of preferential amino acids in sample; obtain racemic mixture of hydantoin, incubate with genetically engineered microorganism, recover amino acids | ENIRICERCHE S.P.A. (IT) | 2003-05-20 | — | — | US | disclosed |
| EP-0775748-B1 | Preparation of D-alpha-amino acids, using bacteria transformed with the carbamoylase-hydantoinase operon | ENITECNOLOGIE SPA (IT) | 2002-11-20 | — | — | EP | disclosed |
| US-5877002-A | ENZYME FROM AGROBACTERIUM RADIOBACTER WITH AMINO ACID SUBSTITUTIONS, FOR EFFICIENT PRODUCTION OF D-ALPHA AMINO ACIDS USED IN CHEMICAL INTERMEDIATES FOR SWEETNERS, INSECTICIDES, CEPHALOSPORINS, PENICILLINS | ENIRICERCHE S.P.A. (IT) | 1999-03-02 | — | — | US | disclosed |
| US-5877003-A | NUCLEOTIDE SEQUENCE FOR ENZYME USED TO EFFICIENTY PRODUCE D-ALPHA AMINO ACIDS; USED AS CHEMICAL INTERMEDIATES FOR SWEETENERS, INSECTICIDES AND SEMI-SYNTHETIC PENICILLINS AND CEPHALOSPORINS | ENIRICERCHE S.P.A (IT) | 1999-03-02 | — | — | US | disclosed |
| US-5869298-A | Stable mutants of D-N-α-carbamoylase and process for preparing D-α-amino acids | ENIRICERCHE S.P.A. (IT) | 1999-02-09 | — | — | US | disclosed |
| EP-0677585-A1 | Process for the production of D-alpha-amino acids | ENIRICERCHE S.p.A. (IT) | 1995-10-18 | — | — | EP | disclosed |
| EP-0647630-A1 | Process for producing 5-arylhydantoins | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-04-12 | — | — | EP | disclosed |
| WO-1988005653-A1 | TOPICAL COMPOSITION FOR STIMULATING HAIR GROWTH WITH STABLE FREE RADICALS | PROCTOR PETER H (US) | 1988-08-11 | — | — | WO | disclosed |
| US-4418146-A | CBS 303.80 OR CBS 363.50 THERMOPHILIC, NON-SPORULATING STRAINS | BASF AKTIENGESELLSCHAFT (DE) | 1983-11-29 | — | — | US | disclosed |
| US-4281009-A | SEDATIVES, ANALGESICS, ANTIULCER AGENTS, A HYPNOTIC AND ANTIHYPERTENSIVE AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | disclosed |
| US-4065353-A | Method for the preparation of D-carbamyl aminoacids and the corresponding D-aminoacids | SNAMPROGETTI, S.P.A. (IT) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240390488-A1 | METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND MEK INHIBITORS | CD274, PDCD1, PDCD1LG2 | ALDH1A1 2289/4885MAPT 3861/4885LMNA 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.