Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17274266 | 0.95 | MGLL (0.47) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL12130707 | 0.81 | ALDH1A1 (0.43) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL18938235 | 0.80 | MGLL (0.49) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL14513914 | 0.80 | MGLL (0.49) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL12130704 | 0.80 | MGLL (0.42) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL1972561 | 0.79 | GSK3B (0.43) | MGLLALDH1A1HPGDMAPTRAB9A | |
| SCHEMBL8433659 | 0.79 | MGLL (0.48) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL8432085 | 0.79 | MGLL (0.48) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL8432091 | 0.79 | MGLL (0.48) | MGLLTSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL12130708 | 0.79 | MGLL (0.41) | MGLLTSHRHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420773-A1 | AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS | Neurochem (International) Limited (CH) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003017994-A1 | AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2003-03-06 | — | — | WO | disclosed |