Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 2/20 | 0.57 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | NQO1 | P15559 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113240 | 0.90 | CYP2C9 (0.69) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL1647638 | 0.88 | CYP2C9 (0.72) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL1647642 | 0.86 | CYP2C9 (0.75) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL5103750 | 0.84 | CYP2C9 (0.66) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL6825815 | 0.83 | VKORC1 (0.61) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL1647664 | 0.81 | NQO1 (0.65) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL3263995 | 0.81 | CYP2C9 (0.67) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL3157772 | 0.81 | CYP2C9 (0.60) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL1649909 | 0.81 | CYP2C9 (0.80) | CYP2C9HSD17B10ALBVKORC1KDM4E | |
| SCHEMBL6827896 | 0.80 | VKORC1 (0.54) | CYP2C9HSD17B10ALBVKORC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383756-A1 | COUMARIN DERIVATIVES TO BE USED AS ANTICOAGULANTS | Arxy Therapeutics (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002085882-A1 | COUMARIN DERIVATIVES TO BE USED AS ANTICOAGULANTS | ARXY THERAPEUTICS (US) | 2002-10-31 | — | — | WO | disclosed |