Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6827832

CC1(CO)COC1.O=C(O)C(F)(F)F

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.64
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31
GABRA4 P48169 1/20 0.31
GABRE P78334 1/20 0.31
GABRA6 Q16445 1/20 0.31
GABRG1 Q8N1C3 1/20 0.31
GABRG3 Q99928 1/20 0.31
GABRQ Q9UN88 1/20 0.31
KCNJ1 P48048 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6002 0.80
Methane SCHEMBL11507333 0.78
Trifluoroacetic Acid SCHEMBL2904301 0.73 HRH4 (0.35) EPHX1
SCHEMBL44597 0.71
SCHEMBL21839289 0.68 EPHX1 (0.73) EPHX1
Trifluoroacetic Acid SCHEMBL3794549 0.67 FAAH (0.40)
Trifluoroacetic Acid SCHEMBL281599 0.67 FAAH (0.40)
Trifluoroacetic Acid SCHEMBL30324569 0.67 FAAH (0.40)
SCHEMBL724637 0.67
Trifluoroacetic Acid SCHEMBL31603504 0.67 HRH4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004076384-A2 PROTECTION OF AMINE AND HYDROXYL GROUPS USING FLUOROACYLATION THE SECRETARY OF STATE FOR DEFENCE (GB) 2004-09-10 WO disclosed