Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828020 | 0.84 | POLB (0.46) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL9039455 | 0.81 | CYP3A4 (0.55) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL14511729 | 0.80 | CYP3A4 (0.56) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL31638876 | 0.79 | CYP3A4 (0.63) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL8870135 | 0.77 | LCK (0.43) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL30892441 | 0.76 | CYP3A4 (0.73) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL14094952 | 0.76 | CYP3A4 (0.68) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL23629456 | 0.76 | LCK (0.42) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL6828398 | 0.76 | CYP3A4 (0.47) | MEN1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL15259689 | 0.76 | KDM4E (0.41) | MEN1KMT2ACYP3A4HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |