Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30629205 | 0.88 | KDM4E (0.50) | MAPTMEN1KMT2ATDP1RECQL | |
| SCHEMBL26768304 | 0.88 | KDM4E (0.50) | MAPTMEN1KMT2ATDP1RECQL | |
| SCHEMBL17108442 | 0.82 | PGR (0.36) | MAPTMEN1KMT2ATDP1RECQL | |
| SCHEMBL26767373 | 0.82 | KDM4E (0.45) | MAPTALDH1A1KDM4EPDK2ESR2 | |
| SCHEMBL26179560 | 0.80 | PDK2 (0.44) | PDK2CNR2CNR1 | |
| SCHEMBL29833582 | 0.80 | PDK2 (0.34) | MAPTTDP1HPGDALDH1A1KDM4E | |
| SCHEMBL346891 | 0.80 | PDK2 (0.34) | MAPTTDP1HPGDALDH1A1KDM4E | |
| SCHEMBL11843462 | 0.78 | ESR1 (0.46) | MAPTMEN1KMT2ATDP1HPGD | |
| SCHEMBL11850892 | 0.76 | FTO (0.40) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL26767358 | 0.76 | MAPT (0.43) | MAPTMEN1KMT2ATDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |
| US-3998962-A | ANTIALLERGEN | BOEHRINGER INGELHEIM GMBH (DT) | 1976-12-21 | — | — | US | disclosed |