Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825466 | 0.90 | PTPN1 (0.40) | PTPN1SMN1; SMN2NPSR1IMPDH2LMNA | |
| SCHEMBL6830384 | 0.84 | ALDH1A1 (0.44) | PTPN1NPSR1IMPDH2ALDH1A1KMT2A | |
| SCHEMBL10483761 | 0.83 | PTPN1 (0.40) | PTPN1SMN1; SMN2NPSR1IMPDH2ALDH1A1 | |
| SCHEMBL6828395 | 0.77 | CA2 (0.36) | PTPN1SMN1; SMN2IMPDH2ALDH1A1TSHR | |
| SCHEMBL8335107 | 0.77 | CYP3A4 (0.38) | PTPN1SMN1; SMN2NPSR1LMNAALDH1A1 | |
| SCHEMBL31643994 | 0.77 | PTPN1 (0.44) | PTPN1SMN1; SMN2NPSR1LMNAALDH1A1 | |
| SCHEMBL13662917 | 0.75 | PTPN1 (0.42) | PTPN1SMN1; SMN2NPSR1LMNAALDH1A1 | |
| SCHEMBL31643691 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2NPSR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6828617 | 0.71 | ERN1 (0.34) | PTPN1IMPDH2 | |
| SCHEMBL14963929 | 0.71 | PTPN1 (0.47) | PTPN1SMN1; SMN2NPSR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |