Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6455911 | 1.00 | MCHR1 (0.56) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Trifluoroacetic Acid SCHEMBL6459529 | 0.84 | NPC1 (0.51) | MCHR1ADRA2AHTR1A | |
| SCHEMBL5530230 | 0.79 | MCHR1 (0.68) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL5530223 | 0.79 | MCHR1 (0.68) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Trifluoroacetic Acid SCHEMBL6456966 | 0.79 | MCHR1 (0.68) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Trifluoroacetic Acid SCHEMBL5670205 | 0.79 | MCHR1 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| Trifluoroacetic Acid SCHEMBL4260895 | 0.79 | MCHR1 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6455920 | 0.78 | MCHR1 (0.54) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6867175 | 0.78 | MCHR1 (0.44) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL6867172 | 0.78 | MCHR1 (0.44) | MCHR1ADRA2AADRA1AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |