Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 12/20 | 0.57 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828384 | 1.00 | UTS2R (0.57) | UTS2RHTR6HTR2CDRD2DRD3 | |
| SCHEMBL6828752 | 0.94 | UTS2R (0.56) | UTS2RHTR6HTR2CDRD2DRD3 | |
| SCHEMBL6829334 | 0.93 | UTS2R (0.56) | UTS2RHTR6HTR2CDRD2DRD3 | |
| SCHEMBL6829339 | 0.93 | UTS2R (0.56) | UTS2RHTR6HTR2CDRD2DRD3 | |
| SCHEMBL6830599 | 0.91 | UTS2R (0.53) | UTS2RHTR6HTR2CDRD2DRD3 | |
| SCHEMBL6828911 | 0.87 | UTS2R (0.58) | UTS2R | |
| SCHEMBL6828914 | 0.87 | UTS2R (0.58) | UTS2R | |
| SCHEMBL6828486 | 0.87 | UTS2R (0.53) | UTS2RHTR6 | |
| SCHEMBL6828484 | 0.87 | UTS2R (0.53) | UTS2RHTR6 | |
| SCHEMBL6829346 | 0.85 | UTS2R (0.55) | UTS2RHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043368-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043368-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |