SCHEMBL6828484

SCHEMBL6828484

CN1CC[C@@H](Oc2cc(NS(=O)(=O)c3cc(Cl)c(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)s3)ccc2Cl)C1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 15/20 0.53
HTR6 P50406 1/20 0.38
SCD O00767 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828486 1.00 UTS2R (0.53) UTS2RHTR6SCD
SCHEMBL6829334 0.87 UTS2R (0.56) UTS2RHTR6SCD
SCHEMBL6829339 0.87 UTS2R (0.56) UTS2RHTR6SCD
SCHEMBL6828386 0.87 UTS2R (0.57) UTS2RHTR6
SCHEMBL6828384 0.87 UTS2R (0.57) UTS2RHTR6
SCHEMBL6828752 0.86 UTS2R (0.56) UTS2RHTR6
SCHEMBL8342418 0.85 UTS2R (0.61) UTS2RSCD
SCHEMBL6829212 0.85 UTS2R (0.50) UTS2R
SCHEMBL6829217 0.85 UTS2R (0.50) UTS2R
SCHEMBL6825907 0.84 UTS2R (0.57) UTS2RHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed