SCHEMBL6828487

SCHEMBL6828487

Cc1ccc(S(=O)(=O)N(C)c2ccc(F)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.82
MCOLN3 Q8TDD5 1/20 0.82
CA12 O43570 1/20 0.69
CA9 Q16790 1/20 0.69
FFAR1 O14842 1/20 0.63
LMNA P02545 1/20 0.62
HTT P42858 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
C5AR1 P21730 1/20 0.56
CNR1 P21554 2/20 0.54
CNR2 P34972 2/20 0.54
AGER Q15109 1/20 0.51
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2008337 0.91 MAPT (1.00) MAPTMCOLN3CA12CA9LMNA
SCHEMBL12070564 0.84 FFAR1 (0.61) MAPTMCOLN3CA12CA9FFAR1
SCHEMBL15374351 0.84 FFAR1 (0.61) MAPTMCOLN3CA12CA9FFAR1
SCHEMBL9201669 0.84 FFAR1 (0.61) MAPTMCOLN3CA12CA9FFAR1
SCHEMBL14469933 0.84 FFAR1 (0.74) MAPTMCOLN3CA12CA9FFAR1
SCHEMBL10186890 0.84 FFAR1 (0.74) MAPTMCOLN3CA12CA9FFAR1
SCHEMBL24125059 0.82 MAPT (0.82) MAPTMCOLN3CA12CA9LMNA
SCHEMBL18031174 0.82 MAPT (0.82) MAPTMCOLN3CA12CA9LMNA
SCHEMBL6828479 0.82 MAPT (0.82) MAPTMCOLN3CA12CA9LMNA
SCHEMBL17174235 0.82 MAPT (0.82) MAPTMCOLN3CA12CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040023938-A1 Sulfonamide derivatives TABUCHI TAKANORI (JP) 2004-02-05 US disclosed
US-6586617-B1 Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2003-07-01 US disclosed
EP-1174028-A1 SULFONAMIDE DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 2002-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040023938-A1 Sulfonamide derivatives FPR1, MRM1, SULT1E1 MAPT 4869/4885MCOLN3 3672/4885CA12 2082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.