Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826000 | 0.91 | KMT2A (0.54) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL3076822 | 0.87 | GAA (0.70) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL15630869 | 0.85 | GAA (0.53) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL7160177 | 0.83 | PTPN1 (0.73) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL30273267 | 0.81 | POLB (0.57) | GAAALDH1A1HPGDCSF1RKMT2A | |
| SCHEMBL6650052 | 0.81 | KMT2A (0.60) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL6828690 | 0.81 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9223541 | 0.81 | GAA (0.81) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL11097456 | 0.81 | GAA (0.58) | GAAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL2492855 | 0.79 | NPC1 (0.68) | GAAALDH1A1SMN1; SMN2HTTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221621-A | Compound, preparation method and application thereof | 暨南大学 | 2024-06-21 | — | — | CN | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |