Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825888 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HTTGAAMAPK1 | |
| SCHEMBL15630869 | 0.83 | GAA (0.53) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL30872533 | 0.82 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2GAAMAPK1RAB9A | |
| SCHEMBL6828581 | 0.81 | GAA (0.56) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL6826056 | 0.81 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPK1RAB9AHPGD | |
| SCHEMBL2069693 | 0.80 | GABRA1 (0.48) | ALDH1A1SMN1; SMN2MAPTHTTKDM4E | |
| SCHEMBL3076822 | 0.77 | GAA (0.70) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL30872535 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPK1RAB9ATDP1TSHR | |
| SCHEMBL2787104 | 0.75 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2MAPTHTTGAA | |
| SCHEMBL15841156 | 0.75 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |