SCHEMBL6828755

SCHEMBL6828755

COc1ccccc1-c1sc(S(=O)(=O)Nc2ccc(C(F)(F)F)c(O[C@@H]3CCN(C)C3)c2)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6828760 1.00 UTS2R (0.61) UTS2R
SCHEMBL8338054 0.93 UTS2R (0.57) UTS2R
SCHEMBL6828687 0.92 UTS2R (0.61) UTS2R
SCHEMBL6828685 0.92 UTS2R (0.61) UTS2R
SCHEMBL6828931 0.92 UTS2R (0.56) UTS2R
SCHEMBL6828927 0.92 UTS2R (0.56) UTS2R
SCHEMBL8338633 0.90 UTS2R (0.62) UTS2R
SCHEMBL6825907 0.89 UTS2R (0.57) UTS2R
SCHEMBL6825909 0.89 UTS2R (0.57) UTS2R
SCHEMBL8341242 0.88 UTS2R (0.51) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO claimed
WO-2004043368-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed