Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 11/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463643 | 1.00 | ADRA2A (0.54) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| Hydrochloric Acid SCHEMBL6456272 | 0.99 | ADRA2A (0.53) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| SCHEMBL6463409 | 0.89 | ADRA2A (0.46) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| SCHEMBL6463406 | 0.89 | ADRA2A (0.46) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| Hydrochloric Acid SCHEMBL6464588 | 0.88 | ADRA2A (0.46) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| SCHEMBL13793992 | 0.81 | NPY5R (0.63) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| Hydrochloric Acid SCHEMBL3942791 | 0.81 | NPY5R (0.62) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| Hydrochloric Acid SCHEMBL3942793 | 0.81 | NPY5R (0.62) | ADRA2AMCHR1NPY5RPRKCQEPHX2 | |
| SCHEMBL13793960 | 0.79 | MCHR1 (0.82) | ADRA2AMCHR1NPY5R | |
| Hydrochloric Acid SCHEMBL3946437 | 0.78 | MCHR1 (0.81) | ADRA2AMCHR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | claimed |