Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013462 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10MEN1CYP2C9 | |
| SCHEMBL28964153 | 0.87 | ALDH1A1 (0.49) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL14593482 | 0.83 | HPGD (0.62) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL10814685 | 0.82 | MAPT (0.38) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL25527300 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL7121659 | 0.77 | KDM4E (0.69) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL11703507 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL25528412 | 0.77 | ALDH1A1 (0.45) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL7035557 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CA12CA1CA2TSHR | |
| SCHEMBL10593035 | 0.77 | POLB (0.40) | ALDH1A1MAPTCYP3A4HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1488698-A1 | Compositions for descreasing intracellular inositol trisphosphate concentration and uses thereof | Bio-Ved Pharmaceuticals, Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-0944309-A4 | COMPOSITIONS FOR MODULATING INTRACELLULAR INOSITOL TRISPHOSPHATE CONCENTRATION AND USES THEREOF | AYURCORE INC (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6083920-A | TREATING NERVOUS SYSTEM DISORDERS BY ADMINISTERING LYSOCEREBROSIDE OR LYSOSPHINGOMYELIN | AYURCORE, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0944309-A1 | COMPOSITIONS FOR MODULATING INTRACELLULAR INOSITOL TRISPHOSPHATE CONCENTRATION AND USES THEREOF | Ayurcore, Inc. (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0750621-B1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1999-07-21 | — | — | EP | disclosed |
| EP-0882065-A2 | NOVEL HUMAN METABOTROPIC GLUTAMATE RECEPTOR | NPS PHARMACEUTICALS, INC. (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5783575-A | CENTRAL NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-07-21 | — | — | US | disclosed |
| EP-0843660-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-27 | — | — | EP | disclosed |
| EP-0842176-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997048724-A2 | HUMAN METABOTROPIC GLUTAMATE RECEPTOR | NPS PHARMACEUTICALS, INC. (US) | 1997-12-24 | — | — | WO | disclosed |
| US-5696148-A | POTENT ANTAGONIST OF METABOTROPIC GLUTAMATE RECEPTORS; TREATING EPILEPSY, PARKINSON'S DISEASE, HUNTINGTON'S DISEASE, BRAIN DISORDER AND ALZHEIMER'S DISEASE | NOVO NORDISK A/S (DK) | 1997-12-09 | — | — | US | disclosed |
| WO-1997022251-A1 | COMPOSITIONS FOR MODULATING INTRACELLULAR INOSITOL TRISPHOSPHATE CONCENTRATION AND USES THEREOF | AYURCORE, INC. (US) | 1997-06-26 | — | — | WO | disclosed |
| WO-1997005109-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | disclosed |
| WO-1997005137-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-02-13 | — | — | WO | disclosed |
| EP-0750621-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-01-02 | — | — | EP | disclosed |
| US-5536721-A | Thieno[2,3-b-indole derivatives and their use for treating central nervous system diseases related to the metabotropic glutamate receptor system | NOVO NORDISK A/S (DK) | 1996-07-16 | — | — | US | disclosed |
| WO-1996015099-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-05-23 | — | — | WO | disclosed |
| WO-1996015100-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-05-23 | — | — | WO | disclosed |
| WO-1995025110-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-09-21 | — | — | WO | disclosed |