Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828189 | 0.90 | ERN1 (0.52) | ERN1PRKDCALDH1A1TRIM24TYR | |
| SCHEMBL6828147 | 0.79 | ERN1 (0.46) | ERN1PRKDCALDH1A1TRIM24TYR | |
| SCHEMBL120483 | 0.79 | ALDH1A1 (0.56) | ERN1PRKDCALDH1A1TRIM24TYR | |
| SCHEMBL31411394 | 0.78 | ERN1 (0.44) | ERN1PRKDCALDH1A1TRIM24TYR | |
| SCHEMBL29048895 | 0.78 | ERN1 (0.58) | ERN1PRKDCALDH1A1TRIM24TYR | |
| SCHEMBL6828133 | 0.76 | LCK (0.41) | ALDH1A1KDM4EMAPTESR2LMNA | |
| SCHEMBL629648 | 0.76 | ALDH1A1 (0.61) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL10861186 | 0.76 | ALDH1A1 (0.61) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL1119262 | 0.73 | PRKDC (0.50) | ERN1PRKDCALDH1A1TRIM24TYR | |
| SCHEMBL23762870 | 0.73 | ERN1 (0.59) | ERN1PRKDCALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |