Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15989607 | 0.82 | LCK (0.52) | LCKFYNKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL4634919 | 0.77 | AKR1C3 (0.50) | KDM4EPOLBSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12837795 | 0.77 | SMN1; SMN2 (0.54) | KDM4EPOLBSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL6829006 | 0.76 | ERN1 (0.44) | KDM4EALDH1A1LMNAMAPTESR2 | |
| SCHEMBL15517008 | 0.76 | LCK (0.55) | LCKFYNKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL1809647 | 0.76 | LCK (0.46) | LCKFYNKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL31457973 | 0.75 | LCK (0.44) | LCKFYNKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL17694370 | 0.73 | LCK (0.44) | LCKFYNKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL9082613 | 0.73 | ALDH1A1 (0.51) | LCKFYNKDM4EHPGDALDH1A1 | |
| SCHEMBL28928501 | 0.70 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |