Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.43 |
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | TGM2 | P21980 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850716 | 0.81 | THRB (0.46) | THRBTHRATSHRMEN1KMT2A | |
| SCHEMBL13806705 | 0.80 | THRB (0.56) | THRBTHRATSHRMEN1KMT2A | |
| SCHEMBL17791314 | 0.80 | THRB (0.51) | THRBTHRATSHRTGM2MEN1 | |
| SCHEMBL10061317 | 0.78 | THRB (0.49) | THRBTSHRHCAR2 | |
| SCHEMBL2556244 | 0.78 | HCAR2 (0.50) | THRBTSHRTGM2MEN1KMT2A | |
| SCHEMBL2427204 | 0.78 | THRB (0.63) | THRBTHRATSHRTGM2MEN1 | |
| SCHEMBL6829098 | 0.78 | TSHR (0.42) | THRBTHRATSHRTGM2MEN1 | |
| SCHEMBL10630810 | 0.78 | THRB (0.49) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL2467984 | 0.77 | TSHR (0.53) | THRBTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL13783898 | 0.77 | THRB (0.70) | THRBTHRATSHRTGM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743515-B1 | DIORGANOPOLYSILOXANES, ORGANOHYDROGENPOLYSILOXANES CONTAINING LESS THAN 20 SIH BONDED HYDROGEN ATOMS AND LESS THAN 12% ARYL GROUPS, ORGANOSILICON COMPOUNDS HAVING EPOXY GROUPS AND HYDROLYZABLE GROUPS AND A HYDROSILYLATION CATALYST | WACKER-CHEMIE GMBH (DE) | 2004-06-01 | — | — | US | disclosed |