Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637392 | 0.84 | THRB (0.47) | THRBTSHRHCAR2ADRB2ADRB1 | |
| SCHEMBL28334078 | 0.84 | THRB (0.49) | THRBTSHRHCAR2LPAR1ADRB2 | |
| SCHEMBL8191319 | 0.81 | CA1 (0.54) | THRBTSHRHCAR2 | |
| SCHEMBL14767584 | 0.80 | MMP12 (0.44) | THRBMMP12MMP13ADRB2ADRB1 | |
| SCHEMBL2258396 | 0.80 | LMNA (0.56) | DPP4MMP12MMP13MMP2MMP9 | |
| Phenol SCHEMBL27954271 | 0.78 | TSHR (0.44) | THRBTSHRADRB2ADRB1ADRB3 | |
| SCHEMBL6829099 | 0.78 | THRB (0.43) | THRBTSHRHCAR2 | |
| SCHEMBL19625554 | 0.78 | CYP1A2 (0.40) | THRBMMP12ADRB2ADRB1ADRB3 | |
| Methacrylic Acid SCHEMBL27741433 | 0.77 | TSHR (0.41) | THRBTSHRADRB2ADRB1ADRB3 | |
| SCHEMBL9656435 | 0.77 | TSHR (0.41) | THRBMMP12MMP2MMP9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412765-A1 | Inkjet recording method, and printed material | FUJIFILM Corporation (JP) | 2012-02-01 | — | — | EP | disclosed |
| EP-1829909-A1 | METHOD FOR PRODUCING BRANCHED POLYETHER RESIN COMPOSITION AND METHOD FOR PRODUCING ACID-PENDANT BRANCHED POLYETHER RESIN COMPOSITION | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-09-05 | — | — | EP | disclosed |