Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831422 | 0.88 | HTR6 (0.47) | HTR6GAASMN1; SMN2SLC2A1LMNA | |
| SCHEMBL6826410 | 0.87 | SLC2A1 (0.55) | HTR6GAASLC2A1LMNAPOLB | |
| SCHEMBL6826779 | 0.85 | HTR6 (0.44) | HTR6GAASMN1; SMN2SLC2A1LMNA | |
| SCHEMBL6925689 | 0.85 | SLC2A1 (0.48) | HTR6GAASLC2A1LMNAATM | |
| SCHEMBL6829377 | 0.83 | HRH3 (0.53) | HTR6GAASLC2A1LMNAKMT2A | |
| SCHEMBL6924887 | 0.78 | ALOX5 (0.52) | HTR6GAASLC2A1LMNAMAPT | |
| SCHEMBL7068535 | 0.76 | HTR6 (0.54) | HTR6SLC2A1LMNATP53PABPC1 | |
| SCHEMBL6826453 | 0.75 | PPARG (0.50) | HTR6GAASMN1; SMN2SLC2A1LMNA | |
| SCHEMBL6924163 | 0.75 | SLC2A1 (0.43) | HTR6GAASLC2A1LMNAKMT2A | |
| SCHEMBL6925801 | 0.74 | KDM4E (0.48) | HTR6SMN1; SMN2SLC2A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |