Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829694 | 0.88 | MEN1 (0.56) | GAAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7065300 | 0.88 | MAPT (0.69) | GAAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6829211 | 0.85 | GRM4 (0.56) | GAAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7129363 | 0.83 | RAB9A (0.52) | GAAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6829504 | 0.81 | SMN1; SMN2 (0.55) | GAAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6829771 | 0.77 | NPC1 (0.50) | GAAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6828985 | 0.76 | SMN1; SMN2 (0.51) | GAAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7193667 | 0.76 | KMT2A (0.55) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6826133 | 0.76 | MAPT (0.49) | GAAKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9356164 | 0.75 | CYP1A2 (0.39) | GAAKDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |