Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CD38 | P28907 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129363 | 0.86 | RAB9A (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6829211 | 0.83 | GRM4 (0.56) | SMN1; SMN2MEN1KMT2ALMNANPC1 | |
| SCHEMBL6829063 | 0.82 | MEN1 (0.60) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6829196 | 0.81 | GAA (0.57) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7065300 | 0.80 | MAPT (0.69) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6829694 | 0.80 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6829771 | 0.77 | NPC1 (0.50) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6829484 | 0.76 | TERT (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29723905 | 0.75 | KDR (0.72) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30643208 | 0.75 | KDR (0.72) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |