Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.51 |
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.49 |
| ▸ | CACNB1 | Q02641 | 7/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.49 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23724037 | 0.84 | HRH1 (0.60) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL3243434 | 0.84 | HRH1 (0.60) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| Hydrochloric Acid SCHEMBL5682715 | 0.83 | HRH1 (0.60) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| Hydrochloric Acid SCHEMBL3818204 | 0.83 | HRH1 (0.60) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL4431100 | 0.82 | SLC6A9 (0.45) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| Hydrochloric Acid SCHEMBL6951585 | 0.81 | HRH1 (0.45) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| Hydrochloric Acid SCHEMBL21462452 | 0.81 | HRH1 (0.45) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| Hydrochloric Acid SCHEMBL5686146 | 0.81 | HRH1 (0.45) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5272706 | 0.80 | HRH1 (0.50) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL6631216 | 0.79 | HRH1 (0.58) | SLC6A9CACNA2D1CACNB1CACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404304-A1 | TABLET COMPRISING CETIRIZINE AND PSEUDOEPHEDRINE | UCB Farchim S.A. (CH) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003002098-A1 | TABLET COMPRISING CETIRIZINE AND PSEUDOEPHEDRINE | UCB, FARCHIM, S.A. (CH) | 2003-01-09 | — | — | WO | disclosed |