Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 1.00 |
| ▸ | KDR | P35968 | 16/20 | 1.00 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829580 | 0.88 | SRC (0.78) | SRCKDR | |
| SCHEMBL6829440 | 0.87 | SRC (1.00) | SRCKDR | |
| SCHEMBL6823949 | 0.87 | SRC (0.77) | SRCKDR | |
| SCHEMBL6831384 | 0.86 | SRC (0.75) | SRCKDR | |
| SCHEMBL6924183 | 0.86 | SRC (0.80) | SRCKDR | |
| Azd-0424 SCHEMBL3202072 | 0.83 | SRC (0.73) | SRCKDR | |
| Azd-0424 SCHEMBL29382167 | 0.83 | SRC (0.73) | SRCKDR | |
| SCHEMBL7132585 | 0.82 | SRC (0.69) | SRCKDR | |
| SCHEMBL6826661 | 0.82 | SRC (0.69) | SRCKDR | |
| SCHEMBL3194213 | 0.81 | SRC (0.69) | SRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108710-A1 | 4-PYRIMIDINYL QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | disclosed |