Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138594 | 0.81 | TSHR (0.42) | TSHRLMNAALDH1A1TDP1ACHE | |
| SCHEMBL11312722 | 0.81 | TSHR (0.42) | TSHRLMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28215177 | 0.76 | HTT (0.52) | TSHRLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL455697 | 0.75 | ALDH1A1 (0.50) | TSHRLMNAHTTALDH1A1TDP1 | |
| SCHEMBL1473759 | 0.75 | ALDH1A1 (0.47) | TSHRLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL4600496 | 0.74 | MEN1 (0.41) | TSHRLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL26325 | 0.72 | TSHR (0.48) | TSHRLMNASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6247825 | 0.72 | HSD17B10 (0.42) | TSHRLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL8811800 | 0.71 | PTPRC (0.39) | TSHRLMNASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL887743 | 0.71 | TSHR (0.48) | TSHRLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253561-B1 | PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER | BOREALIS AG (AT) | 2019-05-08 | — | — | EP | claimed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |