Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767676 | 0.81 | CYP3A4 (0.31) | ALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL3357186 | 0.81 | TSHR (0.51) | ALDH1A1TSHRTDP1ACHELMNA | |
| SCHEMBL28952404 | 0.80 | HSD17B10 (0.47) | ALDH1A1TSHRTDP1ACHECYP3A4 | |
| SCHEMBL1473759 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1ACHECYP3A4 | |
| SCHEMBL6468043 | 0.79 | TSHR (0.42) | ALDH1A1TSHRTDP1ACHECYP3A4 | |
| SCHEMBL26325 | 0.77 | TSHR (0.48) | ALDH1A1TSHRTDP1ACHECYP3A4 | |
| SCHEMBL146835 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHRTDP1ACHECYP3A4 | |
| SCHEMBL57963 | 0.75 | HSD17B10 (0.50) | ALDH1A1TSHRTDP1ACHECYP3A4 | |
| SCHEMBL16005234 | 0.75 | TSHR (0.46) | ALDH1A1TSHRTDP1ACHECYP3A4 | |
| SCHEMBL3591508 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880762-B | Triacylamine derivatives containing 1,8-naphthalimide as well as preparation method and application thereof | 河北农业大学 | 2023-02-21 | — | — | CN | claimed |
| CN-112778125-B | Aryl phenol compound and synthesis method and application thereof | 华东师范大学 | 2023-02-17 | — | — | CN | claimed |
| CN-113880762-A | 1, 8-naphthalimide-containing triacylamine derivatives, and preparation method and application thereof | 河北农业大学 | 2022-01-04 | — | — | CN | claimed |
| CN-112778125-A | Aryl phenol compound and synthesis method and application thereof | 华东师范大学 | 2021-05-11 | — | — | CN | claimed |
| CN-108863935-B | Application of amide compound containing pyrazole ring in preparation of herbicide | 浙江工业大学 | 2020-07-14 | — | — | CN | claimed |
| CN-108117519-B | Amide compound containing pyrazole ring, preparation method and application thereof | 浙江工业大学 | 2020-01-07 | — | — | CN | claimed |
| CN-108586738-A | Synthesis method of linear polyethyleneimine segmented copolymer | 南京工业大学 | 2018-09-28 | — | — | CN | claimed |
| EP-2427426-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-07 | — | — | EP | claimed |
| WO-2016061393-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE | XENOPORT, INC. (US) | 2016-04-21 | — | — | WO | claimed |
| CN-103787802-A | Aryl alkyl thioether compounds and synthesis method thereof | UNIV EAST CHINA NORMAL | 2014-05-14 | — | — | CN | claimed |
| EP-0201203-A2 | Method of treatment of plants with aniline derivatives | MAY & BAKER LIMITED (GB) | 1986-11-12 | — | — | EP | claimed |
| EP-0119892-B1 | HYDROXYL AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS GROWTH FACTORS FOR VEGETABLES AND COMPOSITIONS THEREOF | ROUSSEL-UCLAF (FR) | 1986-08-13 | — | — | EP | claimed |
| US-4521430-A | VASODILATOR, ANTIISCHEMIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1985-06-04 | — | — | US | claimed |
| EP-0128462-A1 | Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1984-12-19 | — | — | EP | claimed |
| EP-0119892-A1 | Hydroxyl amine derivatives, their preparation, their use as growth factors for vegetables and compositions thereof | ROUSSEL-UCLAF (FR) | 1984-09-26 | — | — | EP | claimed |
| EP-0051877-B1 | CARBAMOYLOXYISOOXAZOLE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1984-09-05 | — | — | EP | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| EP-0021058-A2 | Derivatives of benzothienothiazine, their use, process and intermediates for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-01-07 | — | — | EP | claimed |
| US-4090020-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-16 | — | — | US | claimed |