Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.54 |
| ▸ | PDE4A | P27815 | 19/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21051103 | 0.87 | PDE4A (0.61) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6708835 | 0.87 | PDE4A (0.61) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6826639 | 0.80 | PDE4A (0.67) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6129891 | 0.78 | PDE4A (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7123232 | 0.77 | PDE4B (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3180415 | 0.74 | PDE4A (0.80) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7420740 | 0.73 | PDE4A (0.66) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3177887 | 0.73 | PDE4A (0.76) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3165774 | 0.72 | PDE4A (0.67) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6323001 | 0.72 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740765-B1 | DECARBOXYLATING DIESTER | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | disclosed |