Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CEL | P19835 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827998 | 0.79 | TDP1 (0.49) | CYP1B1STSMAPTHSP90AA1KMT2A | |
| SCHEMBL9765298 | 0.79 | CA1 (0.45) | CYP1B1STSMAPTKMT2ATDP1 | |
| SCHEMBL6827603 | 0.79 | TDP1 (0.49) | CYP1B1STSMAPTHSP90AA1KMT2A | |
| SCHEMBL6824269 | 0.79 | CYP1B1 (0.40) | CYP1B1STSMAPTHSP90AA1GAA | |
| SCHEMBL6829397 | 0.79 | CYP1B1 (0.40) | CYP1B1STSMAPTHSP90AA1GAA | |
| SCHEMBL6829613 | 0.77 | TDP1 (0.50) | CYP1B1STSMAPTKMT2ATDP1 | |
| SCHEMBL6829521 | 0.77 | CYP1B1 (0.38) | CYP1B1STSMAPTHSP90AA1GAA | |
| SCHEMBL31266000 | 0.75 | CYP1B1 (0.45) | CYP1B1STSMAPTCELDAO | |
| SCHEMBL10161220 | 0.75 | ADCY8 (0.38) | CYP1B1STS | |
| SCHEMBL18696087 | 0.74 | CYP1B1 (0.46) | CYP1B1STSMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |