Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826427 | 0.86 | MRGPRX4 (0.56) | RAB9ANPC1MRGPRX4ATML3MBTL1 | |
| SCHEMBL6829550 | 0.83 | MRGPRX4 (0.54) | RAB9ANPC1MRGPRX4ATML3MBTL1 | |
| SCHEMBL6829566 | 0.83 | MRGPRX4 (0.54) | RAB9ANPC1MRGPRX4ATML3MBTL1 | |
| SCHEMBL6619558 | 0.83 | MRGPRX4 (0.56) | RAB9ANPC1MRGPRX4ATML3MBTL1 | |
| SCHEMBL7131595 | 0.77 | MRGPRX4 (0.57) | RAB9ANPC1MRGPRX4ATML3MBTL1 | |
| SCHEMBL6828653 | 0.77 | MRGPRX4 (0.64) | MRGPRX4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12056563 | 0.77 | GCGR (0.47) | RAB9ANPC1ATML3MBTL1LMNA | |
| SCHEMBL3585436 | 0.76 | MRGPRX4 (0.49) | RAB9ANPC1MRGPRX4ATML3MBTL1 | |
| SCHEMBL16812822 | 0.76 | MRGPRX4 (0.57) | RAB9ANPC1MRGPRX4ATML3MBTL1 | |
| SCHEMBL7128455 | 0.76 | MRGPRX4 (0.55) | RAB9ANPC1MRGPRX4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |