Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826144 | 0.84 | MRGPRX4 (0.78) | MRGPRX4TP53 | |
| SCHEMBL6826427 | 0.82 | MRGPRX4 (0.56) | MRGPRX4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7131595 | 0.82 | MRGPRX4 (0.57) | MRGPRX4LMNATP53 | |
| SCHEMBL7128455 | 0.80 | MRGPRX4 (0.55) | MRGPRX4KDM4ELMNATP53 | |
| SCHEMBL6829550 | 0.80 | MRGPRX4 (0.54) | MRGPRX4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6829566 | 0.80 | MRGPRX4 (0.54) | MRGPRX4ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6619558 | 0.79 | MRGPRX4 (0.56) | MRGPRX4KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7129725 | 0.79 | MRGPRX4 (0.54) | MRGPRX4HRH3MEN1KMT2A | |
| SCHEMBL22480846 | 0.78 | MRGPRX4 (1.00) | MRGPRX4KDM4EKMT2A | |
| SCHEMBL6829631 | 0.77 | RAB9A (0.57) | MRGPRX4ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |