Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282741 | 0.96 | LMNA (0.47) | LMNACYP19A1MAPTKDM4ECYP3A4 | |
| SCHEMBL14659690 | 0.81 | CYP19A1 (0.46) | LMNACYP19A1MAPTKDM4ECYP3A4 | |
| SCHEMBL21045001 | 0.81 | CYP19A1 (0.42) | LMNACYP19A1MAPTKDM4ECYP3A4 | |
| SCHEMBL7679108 | 0.80 | LMNA (0.59) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL489581 | 0.78 | LMNA (0.59) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL2010436 | 0.78 | LMNA (0.59) | LMNACYP19A1MAPTKDM4ECYP3A4 | |
| SCHEMBL16958037 | 0.77 | LMNA (0.46) | LMNACYP19A1MAPTKDM4ECYP3A4 | |
| SCHEMBL9019388 | 0.75 | TOP1 (0.49) | LMNAMAPTKDM4EMEN1TP53 | |
| SCHEMBL11196485 | 0.75 | CA12 (0.51) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL18371643 | 0.75 | CYP19A1 (0.38) | LMNACYP19A1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743889-B1 | 3,5-BIS(4-FLUOROBENZOYL)PHENOL WITH 4-FLUORO-4'-HYDROXY-BENZOPHENONE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2004-06-01 | — | — | US | disclosed |