Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332622 | 0.89 | TUBB4A (0.50) | TOP1HTTALDH1A1MAPTKMT2A | |
| SCHEMBL28468360 | 0.82 | TOP1 (0.47) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL9679799 | 0.78 | TSHR (0.55) | TOP1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL8765619 | 0.77 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL8765614 | 0.77 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL10053943 | 0.77 | TOP1 (0.53) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL10404868 | 0.76 | CYP4F2 (0.46) | TOP1HTTKDM4EALDH1A1BLM | |
| SCHEMBL6829778 | 0.75 | LMNA (0.43) | HTTKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL7282741 | 0.75 | LMNA (0.47) | HTTKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8779405 | 0.75 | TOP1 (0.51) | TOP1HTTKDM4EALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150507-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR PRODUCING THE SAME AND COMPOSITIONS CONTAINING THEM | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-05 | — | — | EP | claimed |
| US-4888332-A | ANTIBIOTICS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-19 | — | — | US | claimed |
| EP-0150507-A2 | Cephalosporin derivatives, processes for producing the same and compositions containing them | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | claimed |
| EP-0700908-A1 | 1-Arylpyrimidine derivatives and pharmaceutical use thereof | JAPAN ENERGY CORPORATION (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |