Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15922604 | 0.74 | ALOX5AP (0.34) | MEN1KMT2AAPAF1 | |
| SCHEMBL10583804 | 0.72 | CCR1 (0.35) | LMNACCR1CCR5CCR8PMP22 | |
| SCHEMBL10017439 | 0.71 | EDNRB (0.37) | MEN1KMT2ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL3325273 | 0.70 | KDM4E (0.35) | KMT2AKDM4EHTT | |
| SCHEMBL10340174 | 0.70 | — | — | |
| SCHEMBL19073173 | 0.69 | NOS3 (0.31) | — | |
| SCHEMBL10048540 | 0.69 | SCN9A (0.47) | MEN1KMT2AKDM4E | |
| SCHEMBL8958798 | 0.69 | SCN9A (0.33) | — | |
| SCHEMBL153025 | 0.69 | — | — | |
| SCHEMBL7013251 | 0.69 | KDM4E (0.46) | MEN1KMT2ARAB9AHSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199679-A | Industrial preparation method of lamivudine | 吉斯凯(苏州)制药有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-105461772-B | A kind of preparation method of Trifluridine intermediate and Trifluridine | 国药心制药有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-105461772-A | Trifluridine intermediate and preparation method of trifluridine | SINOPHARM A-THINK PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-1191265-C | Process for preparing trifluorothymidine derivatives | MITSUI CHEMICALS INC (JP) | 2005-03-02 | — | — | CN | claimed |
| CN-1366530-A | Process for preparing trifluorothymidine derivatives | MITSUI CHEMICALS INC (JP) | 2002-08-28 | — | — | CN | claimed |
| JP-59029699-A | — | — | None | — | — | JP | disclosed |
| CN-117887452-A | Preparation method of rare earth up-conversion nano particles, product thereof and application of rare earth up-conversion nano particles in preparation of photopolymerization hydrogel and drug release | 中国药科大学 | 2024-04-16 | — | — | CN | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| CN-116199679-A | Industrial preparation method of lamivudine | 吉斯凯(苏州)制药有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-116199679-A | Industrial preparation method of lamivudine | 吉斯凯(苏州)制药有限公司 | 2023-06-02 | — | — | CN | disclosed |
| EP-4022059-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-07-06 | — | — | EP | disclosed |
| CN-102612369-A | Antitumor effect potentiator | TAIHO PHARMACEUTICAL CO LTD | 2012-07-25 | — | — | CN | disclosed |
| CN-102056905-A | Novel uracil compound having human deoxyuridine triphosphatase inhibitory activity or salt thereof | TAIHO PHARMACEUTICAL CO LTD | 2011-05-11 | — | — | CN | disclosed |
| CN-1191265-C | Process for preparing trifluorothymidine derivatives | MITSUI CHEMICALS INC (JP) | 2005-03-02 | — | — | CN | disclosed |
| EP-1372659-A1 | SUBSTANCES FOR USE IN THERAPY OF DISEASES THAT ARE CAUSED BY HIGHLY PROLIFERATIVE CELLS | Schmalz, Hans-Günther (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002080923-A1 | SUBSTANCES FOR USE IN THERAPY OF DISEASES THAT ARE CAUSED BY HIGHLY PROLIFERATIVE CELLS | UNIVERSITÄTSKLINIKUM CHARITÈ (DE) | 2002-10-17 | — | — | WO | disclosed |
| CN-1366530-A | Process for preparing trifluorothymidine derivatives | MITSUI CHEMICALS INC (JP) | 2002-08-28 | — | — | CN | disclosed |
| EP-0274867-A2 | Pharmaceutically active compounds | SCHERING CORPORATION (US) | 1988-07-20 | — | — | EP | disclosed |
| JP-S5929699-A | ETHER DERIVATIVE OF 2'-DEOXY-5-FLUOROURIDINE, ITS PREPARATION, AND ANTITUMOR AGENT CONTAINING IT | FUNAI CORP | 1984-02-16 | — | — | JP | disclosed |