Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567338 | 0.84 | EPHX2 (0.42) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL5042357 | 0.83 | NPC1 (0.47) | KMT2AMEN1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL31465075 | 0.83 | NPC1 (0.47) | KMT2AMEN1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28918169 | 0.81 | HPGD (0.39) | PKMCASP6KMT2AMEN1HPGD | |
| SCHEMBL3610251 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9AHSD17B10TP53 | |
| SCHEMBL3610245 | 0.81 | HTR6 (0.37) | KMT2AMEN1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL4512370 | 0.74 | CYP1A2 (0.37) | CYP1A2 | |
| SCHEMBL4512373 | 0.72 | ALDH1A1 (0.42) | KMT2AMEN1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL4029362 | 0.72 | ALDH1A1 (0.44) | HPGDKDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL28493380 | 0.72 | HTR6 (0.41) | CASP6KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737547-B1 | Compositions containing and methods of using N-acyl-1H-aminoindenes | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2004-05-18 | — | — | US | claimed |
| WO-2000038673-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING N-ACYL-1H-AMINOINDENES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2000-07-06 | — | — | WO | claimed |
| CN-109715605-A | Process for preparing carotenoid monoesters | 巴斯夫欧洲公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109715598-A | Process for preparing carotenoid monoesters | 巴斯夫欧洲公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109715638-A | The method for preparing the structural unit phosphonium salt ester as carotenoid | 巴斯夫欧洲公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109689610-A | The method for preparing 12 '-apocarotenal esters of the structural unit as carotenoid | 巴斯夫欧洲公司 | 2019-04-26 | — | — | CN | disclosed |
| US-6737547-B1 | Compositions containing and methods of using N-acyl-1H-aminoindenes | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2004-05-18 | — | — | US | disclosed |
| WO-2000038673-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING N-ACYL-1H-AMINOINDENES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2000-07-06 | — | — | WO | disclosed |