Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | Q9HBH1 | 1/20 | 0.33 | |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614630 | 0.78 | PLA2G2A (0.38) | EPHX1MEN1FAAHMAPK1KMT2A | |
| SCHEMBL24942562 | 0.77 | MEN1 (0.47) | EPHX1MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11934364 | 0.76 | MEN1 (0.46) | EPHX1MEN1FAAHMAPK1KMT2A | |
| SCHEMBL14508779 | 0.75 | CA12 (0.39) | EPHX1CA12CA1CA9ALDH1A1 | |
| SCHEMBL3983529 | 0.74 | MEN1 (0.44) | EPHX1MEN1FAAHMAPK1KMT2A | |
| SCHEMBL11688621 | 0.74 | NPSR1 (0.42) | MEN1MAPK1KMT2AHDAC6ALDH1A1 | |
| SCHEMBL16068293 | 0.72 | CA12 (0.40) | EPHX1CA12CA1CA9ALDH1A1 | |
| SCHEMBL14242749 | 0.72 | ZDHHC20 (0.44) | MEN1FAAHKMT2ACA12CA1 | |
| SCHEMBL6830439 | 0.71 | MEN1 (0.42) | EPHX1MEN1FAAHMAPK1KMT2A | |
| SCHEMBL7684384 | 0.71 | EPHX1 (0.52) | EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809108-B1 | SELECTIVE MUSCARINIC M3 RECEPTOR ANTAGONTS; REDUCED SIDE EFFECTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| US-4925849-A | DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | disclosed |