Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGAV | P06756 | 2/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827368 | 0.83 | MAPT (0.47) | MAPTHTTITGB3ITGAVITGB1 | |
| Hydrochloric Acid SCHEMBL2238159 | 0.78 | ITGB3 (0.64) | MAPTHTTITGB3ITGAVITGB1 | |
| SCHEMBL196636 | 0.78 | ITGB3 (0.64) | MAPTHTTITGB3ITGAVITGB1 | |
| SCHEMBL4433189 | 0.76 | ITGB3 (0.53) | MAPTHTTITGB3ITGAVITGB1 | |
| SCHEMBL3205146 | 0.75 | ITGB3 (0.66) | MAPTHTTITGB3ITGAVITGB1 | |
| SCHEMBL31139405 | 0.75 | ITGB3 (0.66) | MAPTHTTITGB3ITGAVITGB1 | |
| SCHEMBL29712673 | 0.75 | MAPT (0.53) | MAPTHTTHPGDPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL10912163 | 0.74 | ITGB3 (0.64) | MAPTHTTITGB3ITGAVITGB1 | |
| SCHEMBL8707595 | 0.74 | MAPT (0.61) | MAPTHTTITGB3ITGAVITGB1 | |
| SCHEMBL13948424 | 0.72 | MAPT (0.60) | MAPTHTTITGB3ITGAVITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743940-B2 | MICROBIOCIDES | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-06-01 | — | — | US | disclosed |
| US-20020115881-A1 | 4-aminobut-2-ynecarboxylic acid derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2002-08-22 | — | — | US | disclosed |
| EP-1215198-A1 | 4-Aminobut-2-yne carboxylic acid derivatives and their use as antimicrobial agents | Ciba SC Holding AG (CH) | 2002-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115881-A1 | 4-aminobut-2-ynecarboxylic acid derivatives | DDC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NDC1 | MAPT 4624/4885HTT 4620/4885ITGB3 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.