SCHEMBL6830738

SCHEMBL6830738

c1cc(-c2ccon2)no1.c1coc(-c2ncco2)n1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HPGDS O60760 1/20 0.39
LTA4H P09960 1/20 0.38
BRD4 O60885 1/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 1/20 0.33
CHRM1 P11229 1/20 0.33
ALDH1A1 P00352 1/20 0.31
CHRNA7 P36544 1/20 0.30
CHRNA10 Q9GZZ6 1/20 0.30
CHRNA9 Q9UGM1 1/20 0.30
PIN1 Q13526 1/20 0.30
MDM2 Q00987 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27594120 0.91 CYP1A2 (0.40) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL100765 0.78 HPGDS (0.46) HPGDSLTA4HBRD4CHRNA7CHRNA10
SCHEMBL3082762 0.78 NPC1 (0.42) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL27740433 0.77 CYP1A2 (0.30) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL28934089 0.77
SCHEMBL27804942 0.76 CYP1A2 (0.31) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL27867248 0.76 CYP1A2 (0.31) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL9131737 0.74 HPGDS (0.32) CYP1A2CYP2D6CYP19A1CYP2C9CYP2C19
SCHEMBL1245666 0.70 KDM4E (0.61) CYP1A2CYP2C9CYP2C19NPC1RAB9A
SCHEMBL30564803 0.70 KDM4E (0.61) CYP1A2CYP2C9CYP2C19NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed