Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CCR1 | P32246 | 3/20 | 0.61 |
| ▸ | CCR5 | P51681 | 3/20 | 0.61 |
| ▸ | CCR8 | P51685 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.61 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | TP53 | P04637 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30564803 | 1.00 | KDM4E (0.61) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL28934089 | 0.86 | — | — | |
| Dipyridyl SCHEMBL809479 | 0.78 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1181563 | 0.78 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL9299834 | 0.78 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL8685663 | 0.78 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL7732129 | 0.78 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3082762 | 0.78 | NPC1 (0.42) | KDM4EPOLBCYP1A2NPC1RAB9A | |
| Dipyridyl SCHEMBL3711450 | 0.78 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29351528 | 0.78 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105586030-A | Organic Light-Emitting Device | SAMSUNG DISPLAY CO LTD | 2016-05-18 | — | — | CN | claimed |
| CN-102369200-A | Derivatives of azaspiranyl-alkylcarbamates of 5-member heterocyclic compounds, preparation thereof and therapeutic use thereof | SANOFI SA | 2012-03-07 | — | — | CN | claimed |
| CN-102216291-A | Carbamate derivatives containing alkyl-heterocycles, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-10-12 | — | — | CN | claimed |
| CN-102164920-A | Alkylthiazole carbamate derivatives, method for the production thereof and use thereof as FAAH enzyme inhibitors | SANOFI AVENTIS | 2011-08-24 | — | — | CN | claimed |
| CN-101959884-A | 6-heterocyclic imidazo [1, 2-alpha ] pyridine-2-carboxamide derivatives, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-01-26 | — | — | CN | claimed |
| CN-101918409-A | The diazabicycloalkane derivatives of biaryl substituted | ABBOTT LAB | 2010-12-15 | — | — | CN | claimed |
| CN-100497326-C | 1-piperazine-and 1-homopiperazine-carboxylate derivatives, preparation and therapeutic use thereof | SANOFI AVENTIS (FR) | 2009-06-10 | — | — | CN | claimed |
| CN-101351495-A | fatty acid amide hydrolase inhibitors | ORGANON NV (NL) | 2009-01-21 | — | — | CN | claimed |
| CN-1968950-A | Pyridinylisoxazole compounds and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2007-05-23 | — | — | CN | claimed |
| EP-1758896-A1 | PYRIDINYL-ISOXAZOLES AND THEIR USE AS HERBICIDES | Bayer CropScience GmbH (DE) | 2007-03-07 | — | — | EP | claimed |
| WO-2005123726-A1 | PYRIDINYL-ISOXAZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2005-12-29 | — | — | WO | claimed |
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2005-12-22 | — | — | US | claimed |
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| US-20230271941-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-31 | — | — | US | disclosed |
| US-11576914-B2 | Drug for treating or preventing disorder caused by TGF-β signaling, and application thereof | THE DOSHISHA (JP) | 2023-02-14 | — | — | US | disclosed |
| US-11576914-B2 | Drug for treating or preventing disorder caused by TGF-β signaling, and application thereof | THE DOSHISHA (JP) | 2023-02-14 | — | — | US | disclosed |
| WO-2001019821-A1 | BENZISOXAZOLYL-, PYRIDOISOXAZOLYL- AND BENZTHIENYL-PHENOXY DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| CN-1241184-A | Indole derivatives for the treatment of osteoporosis | SMITHKLINE BEECHAM SPA (IT) | 2000-01-12 | — | — | CN | disclosed |
| CN-1200117-A | Phenylacetic acids, processes for their preparation and agents containing them | BASF AG (DE) | 1998-11-25 | — | — | CN | disclosed |
| CN-1177957-A | Indole derivatives for the treatment of osteoporosis | SMITHKLINE BEECHAM SPA (IT) | 1998-04-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271941-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | KDM4E 3761/4885LMNA 2339/4885CCR1 2064/4885 |
| US-11576914-B2 | Drug for treating or preventing disorder caused by TGF-β signaling, and application thereof | TGFBR1, FIBP, TGFB1 | KDM4E 991/4885LMNA 2922/4885CCR1 939/4885 |
| US-20050282707-A1 | Pyridinylisoxazoles and their use as herbicides | PRDX1, CYP4X1, PRDX4 | KDM4E 2037/4885LMNA 2335/4885CCR1 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.