Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 4/20 | 0.32 |
| ▸ | UTRN | P46939 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 2/20 | 0.31 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831619 | 0.87 | ADA (0.42) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL6831266 | 0.83 | ADA (0.42) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL4584885 | 0.77 | ADA (0.51) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL4584332 | 0.74 | ADA (0.37) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL4584335 | 0.74 | ADA (0.37) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL6830883 | 0.72 | ADA (0.42) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL4584109 | 0.71 | ADA (0.46) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL4583760 | 0.69 | HTR3A (0.39) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL4583767 | 0.69 | HTR3A (0.39) | ADABCHEHTR3ACASP3SENP7 | |
| SCHEMBL4583762 | 0.69 | HTR3A (0.39) | ADABCHEHTR3ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474421-A1 | IMIDAZOLE 4-CARBOXAMIDE COMPOUNDS WITH ADENOSINE DEAMINASE INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068768-A1 | IMIDAZOLE 4-CARBOXAMIDE COMPOUNDS WITH ADENOSINE DEAMINASE INHIBITING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-21 | — | — | WO | disclosed |